SCHEMBL9474352

SCHEMBL9474352

Cc1ccc2cc(CC(=O)c3ccc(O)cc3O)ccc2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.74
ESR1 P03372 1/20 0.65
SHBG P04278 1/20 0.65
ESR2 Q92731 1/20 0.65
ALDH1A1 P00352 6/20 0.62
RAB9A P51151 5/20 0.62
HPGD P15428 5/20 0.62
NPC1 O15118 4/20 0.62
KMT2A Q03164 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
MEN1 O00255 3/20 0.62
CYP3A4 P08684 1/20 0.62
ATM Q13315 1/20 0.62
LMNA P02545 5/20 0.58
MAPT P10636 5/20 0.58
GAA P10253 2/20 0.58
HTT P42858 1/20 0.58
ALOX12 P18054 1/20 0.58
TP53 P04637 2/20 0.57
RECQL P46063 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820741 0.86 ESR1 (0.81) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL38652384 0.86 ESR1 (0.81) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL13640734 0.83 ESR1 (0.75) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL13966006 0.80 ESR1 (0.64) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL30503014 0.80 ESR1 (1.00) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL312243 0.80 ESR1 (1.00) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL31511910 0.79 ESR1 (0.77) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL3068438 0.79 ESR1 (0.77) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL31511913 0.77 SMN1; SMN2 (0.70) ALOX5ESR1SHBGESR2ALDH1A1
SCHEMBL485061 0.77 ESR1 (0.65) ALOX5ESR1SHBGESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5112552-A None JP disclosed
JP-H05112552-A BENZOPYRAN DERIVATIVE AND ITS PRODUCTION TANABE SEIYAKU CO LTD 1993-05-07 JP disclosed