Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYBB | P04839 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.54 |
| ▸ | MARK4 | Q96L34 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220378 | 0.87 | NOX1 (0.70) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL9778312 | 0.81 | NOX1 (0.70) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL1509893 | 0.79 | NOX1 (0.84) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL22960679 | 0.79 | KCNH2 (0.62) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL343025 | 0.78 | NOX1 (0.57) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL28117966 | 0.78 | NOX1 (0.81) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL4670416 | 0.77 | NOX1 (0.79) | NOX1BCHEACHEMEN1KMT2A | |
| Urea SCHEMBL27590816 | 0.77 | NOX1 (0.79) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL236458 | 0.76 | NOX1 (1.00) | NOX1BCHEACHEMEN1KMT2A | |
| SCHEMBL29384266 | 0.76 | NOX1 (1.00) | NOX1BCHEACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194544-A | Acrylic polymers containing phenothiazine rings or similar fused heterocycle rings, lenses | UNIVERSITY OF FLORIDA (US) | 1993-03-16 | — | — | US | disclosed |
| US-4985559-A | Used for Contact and Intraocular Lenses; Phenothiazine (Meth)acrylates or (Meth)acrylamide derivatives | UNIVERSITY OF FLORIDA (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0344244-A1 | UV ABSORBING VINYL MONOMERS AND POLYMERS AND OCULAR IMPLANTS PREPARED THEREFROM | THE UNIVERSITY OF FLORIDA (US) | 1989-12-06 | — | — | EP | disclosed |
| WO-1989003386-A1 | UV ABSORBING VINYL MONOMERS AND POLYMERS AND OCULAR IMPLANTS PREPARED THEREFROM | UNIVERSITY OF FLORIDA (US) | 1989-04-20 | — | — | WO | disclosed |