Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 13/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475487 | 0.86 | PTGES (0.55) | PTGESALOX5FFAR1 | |
| SCHEMBL9476259 | 0.83 | PTGES (0.58) | PTGESALOX5FFAR1 | |
| SCHEMBL9476560 | 0.83 | ALOX5 (0.46) | PTGESALOX5 | |
| SCHEMBL9476517 | 0.79 | FFAR1 (0.41) | PTGESALOX5FFAR1EPHX2 | |
| SCHEMBL9474987 | 0.79 | PTGES (0.61) | PTGESALOX5FFAR1 | |
| SCHEMBL9476552 | 0.77 | HRH3 (0.48) | PTGESALOX5 | |
| SCHEMBL9192563 | 0.74 | PTGES (0.56) | PTGESALOX5 | |
| SCHEMBL9476486 | 0.74 | ALOX5 (0.54) | ALOX5EPHX2 | |
| SCHEMBL9197210 | 0.73 | PTGES (0.58) | PTGESALOX5FFAR1 | |
| SCHEMBL9300024 | 0.73 | ALOX5 (0.43) | ALOX5FFAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |