Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 12/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192515 | 0.88 | HRH3 (0.48) | HRH3ACACBPTGESALOX5CHAT | |
| SCHEMBL9476517 | 0.85 | FFAR1 (0.41) | PTGESALOX5 | |
| SCHEMBL9476560 | 0.84 | ALOX5 (0.46) | ACACBPTGESALOX5 | |
| SCHEMBL9474987 | 0.82 | PTGES (0.61) | PTGESALOX5 | |
| SCHEMBL9475487 | 0.77 | PTGES (0.55) | PTGESALOX5 | |
| SCHEMBL9475172 | 0.77 | PTGES (0.43) | PTGESALOX5 | |
| SCHEMBL9476259 | 0.74 | PTGES (0.58) | PTGESALOX5 | |
| SCHEMBL234203 | 0.73 | HRH3 (0.53) | HRH3ACACBPTGESCHAT | |
| SCHEMBL9195229 | 0.71 | ACACB (0.48) | ACACBPTGESALOX5 | |
| SCHEMBL9193618 | 0.71 | PTGES (0.62) | PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202349-A | Lipoxygenase inhibitors, antiasthatics | GRUENENTHAL GMBH (DE) | 1993-04-13 | — | — | US | disclosed |