Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475474 | 0.86 | MAPT (0.43) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9474908 | 0.85 | ALDH1A1 (0.47) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9474408 | 0.85 | SMN1; SMN2 (0.40) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9475002 | 0.84 | PPARA (0.40) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9476412 | 0.83 | PLK1 (0.50) | LMNAALDH1A1MAPK1TDP1MAPT | |
| SCHEMBL9475464 | 0.82 | MAPT (0.47) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9475853 | 0.80 | NPC1 (0.48) | LMNAALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9474900 | 0.78 | L3MBTL1 (0.45) | ALDH1A1MAPK1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL9475925 | 0.76 | MAPT (0.43) | LMNAALDH1A1ALOX15APEX1MAPK1 | |
| SCHEMBL9474872 | 0.74 | ALDH1A1 (0.44) | LMNAALDH1A1ALOX15APEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243066-A | ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |