Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475925 | 0.86 | MAPT (0.43) | MAPTSMN1; SMN2LMNACYP2C9CYP2C19 | |
| SCHEMBL9475312 | 0.86 | LMNA (0.45) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9474408 | 0.85 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2LMNACYP2C9CYP2C19 | |
| SCHEMBL9478131 | 0.84 | PPARA (0.50) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL9477232 | 0.83 | PLK1 (0.46) | LMNANPC1RAB9ATSHRABCB11 | |
| SCHEMBL9476928 | 0.83 | ALDH1A1 (0.48) | MAPTLMNACYP2C9CYP2C19TSHR | |
| SCHEMBL9475651 | 0.80 | NPC1 (0.51) | MAPTSMN1; SMN2LMNACYP2C9NPC1 | |
| SCHEMBL9475543 | 0.76 | CNR2 (0.46) | MAPTSMN1; SMN2LMNACYP2C9CYP2C19 | |
| SCHEMBL9475743 | 0.76 | TP53 (0.51) | SMN1; SMN2TSHRTP53MAPK1 | |
| SCHEMBL6656142 | 0.76 | SLC13A5 (0.49) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243066-A | ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |