Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506540 | 0.81 | NR1H2 (0.33) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL15564536 | 0.69 | NR1H2 (0.33) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL8701181 | 0.69 | CYP2C19 (0.38) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL4340363 | 0.66 | ESR1 (0.41) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL8509750 | 0.66 | ESR1 (0.41) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL1470831 | 0.66 | NR1H2 (0.53) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL31029241 | 0.66 | ALDH1A1 (0.42) | MAPTTSHR | |
| SCHEMBL30821468 | 0.66 | KCNH3 (0.36) | TSHR | |
| SCHEMBL29759405 | 0.65 | TDP1 (0.40) | MAPTNR1H2NR1H3TSHR | |
| SCHEMBL27150037 | 0.65 | TDP1 (0.40) | MAPTNR1H2NR1H3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024467-A1 | FUNGICIDAL IMIDAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5214139-A | 2-phenanthridonyl-carbapenems | MERCK & CO., INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5208328-A | Intermediates for antibiotics and bactericides | MERCK & CO., INC. (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0509780-A1 | 2-phenanthridonyl carbapenems | MERCK & CO. INC. (US) | 1992-10-21 | — | — | EP | disclosed |
| EP-0509756-A1 | 2-Phenanthridonyl carbapenems having cationizeable substituents | MERCK & CO. INC. (US) | 1992-10-21 | — | — | EP | disclosed |
| US-5157033-A | Controlling methicillin-resistant grampositive Staphylococcus; bactericides | MERCK & CO., INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5153185-A | Antibiotics for methicillin resistant Staphylococcus strains | MERCK & CO., INC. (US) | 1992-10-06 | — | — | US | disclosed |