Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477126 | 0.76 | ATM (0.48) | ATMMEN1KMT2ARAB9ACYP2A6 | |
| SCHEMBL269155 | 0.76 | ATM (0.48) | ATMMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9476641 | 0.72 | ATM (0.44) | ATMMEN1KMT2ARAB9ACYP2A6 | |
| SCHEMBL9476286 | 0.71 | ATM (0.42) | ATMMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1735048 | 0.67 | RAB9A (0.41) | ATMMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3084819 | 0.66 | ATM (1.00) | ATMMEN1KMT2ARAB9ACYP2A6 | |
| SCHEMBL8512795 | 0.65 | ATM (0.50) | ATMMEN1KMT2ARAB9ACYP2A6 | |
| SCHEMBL28205936 | 0.64 | ATM (0.48) | ATMMEN1KMT2ARAB9ACYP2A6 | |
| SCHEMBL24772 | 0.64 | ATM (0.43) | ATMRAB9ANPC1 | |
| SCHEMBL27615068 | 0.63 | ATM (0.57) | ATMMEN1KMT2ARAB9ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0477789-A1 | 1,3-Benzoxazine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |