Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024345 | 0.75 | HTR7 (0.43) | HTR7GPBAR1GABRA5GRM5 | |
| SCHEMBL9024716 | 0.71 | HTR7 (0.53) | HTR7HTTGPBAR1GABRPGABRD | |
| SCHEMBL9445139 | 0.70 | HDAC1 (0.41) | HTR7GRM5HDAC1HDAC8HDAC6 | |
| SCHEMBL9473993 | 0.69 | HTR7 (0.42) | HTR7PTGS1PTGS2GRM5 | |
| SCHEMBL9689077 | 0.68 | DRD2 (0.43) | KCNH2 | |
| SCHEMBL9445273 | 0.66 | HTR7 (0.39) | HTR7GRM5 | |
| SCHEMBL20546704 | 0.63 | HTR7 (1.00) | HTR7GPBAR1 | |
| SCHEMBL10849958 | 0.62 | TSHR (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10342691 | 0.62 | TSHR (0.39) | GAAHTTNPSR1GABRPGABRD | |
| SCHEMBL10342726 | 0.62 | TSHR (0.41) | GAAHTTNPSR1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5180834-A | Antipsychotic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-01-19 | — | — | US | disclosed |