Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025209 | 0.92 | DRD2 (0.43) | DRD2HTR2AHTR2CPARP1PARP2 | |
| Hydrochloric Acid SCHEMBL9024139 | 0.91 | DRD2 (0.43) | DRD2HTR2AHTR2CPARP1PARP2 | |
| SCHEMBL9025050 | 0.87 | HTR2C (0.53) | DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9024955 | 0.86 | HTR2C (0.52) | DRD2HTR2AHTR2C | |
| SCHEMBL9024345 | 0.81 | HTR7 (0.43) | DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL9701571 | 0.79 | HTR2C (0.34) | DRD2HTR2AHTR2CHTR1A | |
| SCHEMBL9024351 | 0.79 | SLC6A2 (0.44) | DRD2HTR2AHTR2C | |
| SCHEMBL9023838 | 0.79 | HTR2C (0.55) | DRD2HTR2AHTR2C | |
| SCHEMBL9445150 | 0.78 | HTR7 (0.41) | DRD2HTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL9023939 | 0.78 | HTR2C (0.54) | DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114936-A | Antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |