Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9140317 | 1.00 | PLA2G4B (0.62) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7484161 | 0.95 | SMN1; SMN2 (0.62) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL9619201 | 0.94 | PLA2G4B (0.56) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL9619334 | 0.94 | PLA2G4B (0.60) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL3801206 | 0.89 | TBXAS1 (0.60) | KDM4ECYP1A2CYP2D6PDE4ASMN1; SMN2 | |
| SCHEMBL13348627 | 0.89 | KDM4E (0.66) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL11566931 | 0.88 | MAPT (0.58) | PLA2G4BTSHRTBXAS1LTA4HLMNA | |
| SCHEMBL11566670 | 0.88 | MAPT (0.58) | PLA2G4BTSHRTBXAS1LTA4HLMNA | |
| SCHEMBL27855929 | 0.88 | TBXAS1 (0.54) | PLA2G4BKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL27855918 | 0.87 | TBXAS1 (0.55) | KDM4ECYP1A2CYP2D6PDE4ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921591-B2 | Process for synthesizing phenylacetic acid by carbonylation of toluene | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2014-12-30 | — | — | US | disclosed |
| US-20130303798-A1 | PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2013-11-14 | — | — | US | disclosed |
| US-5243066-A | ALKYL 2-ARYL-2,2-DIALKOXYACETATES, THE PREPARATION THEREOF AND A METHOD OF USING THEM FOR PREPARING ARYLGLYOXYLIC ESTERS | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303798-A1 | PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE | DDT, HPD, PAH | PLA2G4B 3360/4885KDM4E 962/4885CYP1A2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.