Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477103 | 0.92 | DCTPP1 (0.42) | SMN1; SMN2HPGDMAPK1GAAALDH1A1 | |
| SCHEMBL9477351 | 0.92 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MAPTCACNA1FCACNA1D | |
| SCHEMBL9475146 | 0.87 | PTGDR2 (0.42) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9476368 | 0.86 | TP53 (0.40) | GAAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9475728 | 0.86 | ABL1 (0.41) | GAAALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL9476315 | 0.85 | MAPT (0.41) | SMN1; SMN2HPGDGAAALDH1A1MAPT | |
| SCHEMBL9475602 | 0.84 | MAPT (0.49) | SMN1; SMN2HPGDMAPK1GAAALDH1A1 | |
| SCHEMBL9476024 | 0.83 | ALDH1A1 (0.41) | HPGDGAAALDH1A1CACNA1FCACNA1D | |
| SCHEMBL7272032 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2HPGDMAPK1GAAALDH1A1 | |
| SCHEMBL9476099 | 0.82 | POLB (0.40) | SMN1; SMN2GAAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202330-A | Hypotensive and cardiovascular agent, reduces blood pressure in mammals | E. R. SQUIBB & SONS, INC. (US) | 1993-04-13 | — | — | US | disclosed |