Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 10/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14370506 | 0.93 | P2RX7 (0.55) | CTRB1P2RX7CTSLCTSKCA1 | |
| SCHEMBL3070245 | 0.89 | P2RX7 (0.48) | CTRB1P2RX7CTSLLMNACA1 | |
| SCHEMBL7990303 | 0.87 | P2RX7 (0.47) | CTRB1P2RX7CTSLLMNACTSK | |
| SCHEMBL7990292 | 0.86 | LMNA (0.48) | CTRB1P2RX7LMNACA1CA2 | |
| SCHEMBL3652008 | 0.86 | P2RX7 (0.51) | P2RX7LMNACTSKGAACA1 | |
| SCHEMBL22552853 | 0.86 | P2RX7 (0.51) | P2RX7LMNACTSKGAACA1 | |
| SCHEMBL3652010 | 0.86 | P2RX7 (0.51) | P2RX7LMNACTSKGAACA1 | |
| SCHEMBL27447522 | 0.86 | CTRB1 (0.55) | CTRB1P2RX7CTSLCTSKGAA | |
| SCHEMBL1258429 | 0.86 | ATM (0.56) | P2RX7CTSLLMNACTSKGAA | |
| SCHEMBL1258432 | 0.86 | ATM (0.56) | P2RX7CTSLLMNACTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244905-A | Gastric antisecretory, antipsychotic, appetite suppressants | WARNER-LAMBERT COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1992004348-A1 | N-SUBSTITUTED CYCLOALKYL AND POLYCYCLOAKYL POLYHYDRO-Β-CARBOLINE-PHENYLALANINE-AND PHENETHYLAMINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |