Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9476039 | 0.99 | KMT2A (0.33) | KMT2AMEN1CHEK1CYP1A2CYP3A4 | |
| SCHEMBL9475901 | 0.91 | ACHE (0.38) | MAPK1 | |
| SCHEMBL9477129 | 0.91 | KMT2A (0.32) | KMT2AMEN1CHEK1 | |
| Hydrochloric Acid SCHEMBL9476844 | 0.91 | ACHE (0.37) | MAPK1 | |
| Hydrochloric Acid SCHEMBL9479486 | 0.90 | KMT2A (0.32) | KMT2AMEN1CHEK1 | |
| SCHEMBL9477694 | 0.83 | ABCC4 (0.36) | — | |
| SCHEMBL9476703 | 0.83 | KMT2A (0.33) | KMT2AMEN1CYP2D6HSD17B10 | |
| Hydrochloric Acid SCHEMBL9478051 | 0.83 | ABCC4 (0.36) | — | |
| SCHEMBL9475100 | 0.82 | KMT2A (0.33) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9475282 | 0.82 | KDM4E (0.35) | KMT2AMEN1HSD17B10S1PR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179089-A | Antiallergens, asthma | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-01-12 | — | — | US | claimed |
| EP-0486211-A1 | Isoquinoline derivatives | CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-20 | — | — | EP | claimed |
| JP-4283567-A | — | — | None | — | — | JP | disclosed |
| JP-H04283567-A | NEW COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING NEW COMPOUND AND ITS PRODUCTION | CHINOIN GYOGYSZER V T G RT | 1992-10-08 | — | — | JP | disclosed |