Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9478051 | 0.99 | ABCC4 (0.36) | ABCC4ABCB11CHRM2ADRA2AADORA3 | |
| SCHEMBL9475901 | 0.92 | ACHE (0.38) | ABCC4ABCB11CHRM2ADRA2AADORA3 | |
| SCHEMBL9477129 | 0.91 | KMT2A (0.32) | PDE4A | |
| Hydrochloric Acid SCHEMBL9476844 | 0.91 | ACHE (0.37) | ABCC4ABCB11CHRM2ADRA2AADORA3 | |
| Hydrochloric Acid SCHEMBL9479486 | 0.90 | KMT2A (0.32) | PDE4A | |
| SCHEMBL9478024 | 0.83 | KMT2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL9476039 | 0.83 | KMT2A (0.33) | — | |
| SCHEMBL9479120 | 0.82 | ABCC4 (0.37) | ABCC4ABCB11CHRM2ADRA2AADORA3 | |
| SCHEMBL9476362 | 0.81 | ADRA2A (0.37) | ABCC4ABCB11CHRM2ADRA2AADORA3 | |
| SCHEMBL9476649 | 0.81 | ABCC4 (0.37) | ABCC4ABCB11CHRM2ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179089-A | Antiallergens, asthma | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1993-01-12 | — | — | US | claimed |
| EP-0486211-A1 | Isoquinoline derivatives | CHINOIN Gyògyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-05-20 | — | — | EP | claimed |