Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 7/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183451 | 0.80 | AGTR1 (0.36) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8092930 | 0.79 | LTB4R2 (0.49) | LTB4R2AGTR1 | |
| SCHEMBL9479326 | 0.78 | AGTR1 (0.40) | LTB4R2AGTR1AGTR2PTGDR2 | |
| SCHEMBL9479331 | 0.76 | AGTR1 (0.44) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL18425480 | 0.75 | LTB4R2 (0.69) | LTB4R2AGTR1 | |
| SCHEMBL8700930 | 0.73 | LTB4R2 (0.37) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9479341 | 0.73 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8260354 | 0.72 | LTB4R2 (0.52) | LTB4R2AGTR1 | |
| SCHEMBL443650 | 0.71 | LTB4R2 (0.65) | LTB4R2AGTR1 | |
| SCHEMBL443818 | 0.71 | LTB4R2 (0.59) | LTB4R2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242928-A | Angiotensin II antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-07 | — | — | US | disclosed |