Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482477 | 0.70 | NPSR1 (0.40) | CYP19A1ALDH1A1LMNAHTTMEN1 | |
| SCHEMBL26229895 | 0.68 | THRB (0.52) | CYP19A1CYP17A1THRBCYP2C9ALDH1A1 | |
| SCHEMBL865316 | 0.68 | CYP19A1 (0.43) | CYP19A1CYP17A1THRBCYP2C9ALDH1A1 | |
| SCHEMBL7305803 | 0.67 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL4339903 | 0.66 | CYP19A1 (0.42) | CYP19A1CYP17A1THRBCYP2C9ALDH1A1 | |
| SCHEMBL677286 | 0.66 | P2RX7 (0.44) | CYP19A1CYP17A1ALDH1A1MEN1KMT2A | |
| SCHEMBL8864 | 0.65 | NPSR1 (0.43) | CYP19A1CYP17A1THRBCYP2C9ALDH1A1 | |
| SCHEMBL29757001 | 0.64 | MEN1 (0.60) | ALDH1A1MAPTMEN1KMT2ATSHR | |
| SCHEMBL5672670 | 0.64 | NPSR1 (0.41) | CYP19A1THRBCYP2C9ALDH1A1LMNA | |
| SCHEMBL28347198 | 0.63 | NPSR1 (0.41) | CYP19A1THRBCYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242914-A | 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY, LIMITED (JP) | 1993-09-07 | — | — | US | disclosed |