Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727556 | 0.84 | BCAT1 (0.45) | MAPTTP53THRBNR3C2PGR | |
| SCHEMBL7556723 | 0.80 | MMP12 (0.46) | MMP12MAPTTP53THRBMEN1 | |
| SCHEMBL10491107 | 0.76 | MAPT (0.46) | MMP12MAPTTP53THRBMEN1 | |
| SCHEMBL7563867 | 0.75 | NR3C2 (0.39) | MMP12MAPTTP53THRBNR3C2 | |
| SCHEMBL12808579 | 0.75 | MMP12 (0.41) | MMP12MAPTTP53THRBMEN1 | |
| SCHEMBL12060295 | 0.73 | TP53 (0.57) | MMP12MAPTTP53THRBMEN1 | |
| SCHEMBL10592084 | 0.73 | NR3C2 (0.53) | MMP12MAPTTP53THRBMEN1 | |
| SCHEMBL6617682 | 0.73 | NR3C2 (0.39) | MMP12MAPTTP53THRBKMT2A | |
| SCHEMBL4049030 | 0.73 | MMP12 (0.54) | MMP12MAPTTP53THRBKMT2A | |
| SCHEMBL9477408 | 0.72 | BCAT2 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232898-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0434778-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-03 | — | — | EP | disclosed |
| WO-1990015057-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-12-13 | — | — | WO | disclosed |