Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 10/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 9/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480245 | 0.84 | MMP12 (0.43) | NR3C2PGRTP53MAPTTHRB | |
| SCHEMBL7563867 | 0.78 | NR3C2 (0.39) | NR3C2KIF11POLBNR3C1PGR | |
| SCHEMBL6617682 | 0.78 | NR3C2 (0.39) | NR3C2ALDH1A1SMN1; SMN2KIF11POLB | |
| SCHEMBL7556723 | 0.75 | MMP12 (0.46) | NR3C2ALDH1A1SMN1; SMN2NR3C1PGR | |
| SCHEMBL6627299 | 0.74 | BCAT1 (0.45) | BCAT1BCAT2 | |
| SCHEMBL9427475 | 0.74 | BCAT1 (0.41) | BCAT1BCAT2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9603358 | 0.73 | KIF11 (0.47) | NR3C2ALDH1A1SMN1; SMN2KIF11POLB | |
| SCHEMBL7974838 | 0.72 | NR3C2 (0.44) | BCAT1BCAT2NR3C2ALDH1A1CYP2C9 | |
| SCHEMBL12188289 | 0.71 | BCAT1 (0.46) | BCAT1BCAT2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4049030 | 0.71 | MMP12 (0.54) | NR3C2ALDH1A1SMN1; SMN2PGRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5127935-A | Halogen, phenyl and heterocycle substituents, agricultural use | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0408382-A2 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-01-16 | — | — | EP | disclosed |