Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543436 | 0.82 | TRPV3 (0.31) | — | |
| SCHEMBL9685498 | 0.81 | MEN1 (0.52) | MEN1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL9480616 | 0.81 | LTA4H (0.45) | MEN1KMT2APOLBRAB9A | |
| SCHEMBL1451793 | 0.78 | LTA4H (0.44) | MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL443386 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EPOLBRAB9A | |
| SCHEMBL9686329 | 0.77 | MEN1 (0.44) | MEN1KMT2AKDM4EPOLB | |
| SCHEMBL9687059 | 0.77 | MAPT (0.39) | MEN1KMT2ARAB9A | |
| SCHEMBL9684612 | 0.77 | HTT (0.44) | MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL6544233 | 0.77 | MEN1 (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL9479749 | 0.77 | LTA4H (0.50) | KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247381-B1 | 5-FLUROROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5047521-A | Anticarcinogenic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0247381-A2 | 5-flurorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |