Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340918 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1ADRA2BPTGS1SLC6A2 | |
| SCHEMBL12680868 | 0.80 | P2RX3 (0.52) | ALDH1A1TDP1ADRA2BPTGS1ADORA2A | |
| SCHEMBL12681546 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TDP1ADRA2BPTGS1ADORA2A | |
| SCHEMBL1340917 | 0.79 | HTR1A (0.52) | ALDH1A1SLC6A2HTR1ASLC6A4MAPT | |
| SCHEMBL3161168 | 0.79 | LMNA (0.43) | ALDH1A1TDP1ADRA2BPTGS1ADORA2A | |
| SCHEMBL14354842 | 0.79 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL3149784 | 0.77 | NSD2 (0.40) | ALDH1A1TDP1ADRA2BPTGS1ADORA2A | |
| SCHEMBL1135464 | 0.77 | P2RY1 (0.52) | — | |
| SCHEMBL8464915 | 0.77 | ALDH1A1 (0.47) | ALDH1A1PIN1TDP1ADRA2BPTGS1 | |
| SCHEMBL1307403 | 0.76 | CYP1A2 (0.42) | ALDH1A1SLC6A2CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5274100-A | Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids | CIBA-GEIGY CORPORATION (US) | 1993-12-28 | — | — | US | disclosed |