Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947917 | 1.00 | CYP2C9 (0.45) | CYP2C9CYP2C19HSD17B10PPARAAKR1C3 | |
| SCHEMBL950416 | 0.75 | TRPA1 (0.45) | PPARATSHRSDCBPSDC2 | |
| SCHEMBL5027835 | 0.74 | LMNA (0.43) | CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL949305 | 0.74 | KMO (0.44) | CYP2C9CYP2C19HSD17B10AKR1C3AKR1C2 | |
| SCHEMBL949434 | 0.74 | KMO (0.44) | CYP2C9CYP2C19HSD17B10AKR1C3AKR1C2 | |
| SCHEMBL27670173 | 0.74 | KMO (0.44) | CYP2C9CYP2C19HSD17B10AKR1C3AKR1C2 | |
| Bicarbonate SCHEMBL29074426 | 0.71 | CYP2A6 (0.59) | CYP2C9KMOTSHRCYP2A6 | |
| SCHEMBL11472966 | 0.70 | AKR1C3 (0.63) | AKR1C3AKR1C2TSHR | |
| Ammonia Solution, Strong SCHEMBL11726463 | 0.69 | AKR1C3 (0.61) | AKR1C3AKR1C2TSHR | |
| SCHEMBL949028 | 0.69 | ALOX15 (0.41) | CYP2C9CYP2C19HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | CYP2C9 18/4885CYP2C19 25/4885HSD17B10 821/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | CYP2C9 17/4885CYP2C19 22/4885HSD17B10 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.