Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483370 | 0.83 | MAPT (0.56) | ITGB3ITGA2BPOLB | |
| SCHEMBL7425378 | 0.83 | GAA (0.53) | YAP1 | |
| SCHEMBL9484259 | 0.81 | ATM (0.46) | P2RX7BACE1POLBSYK | |
| SCHEMBL5859750 | 0.80 | P2RX7 (0.55) | YAP1P2RX7BACE1SYK | |
| SCHEMBL20425431 | 0.80 | L3MBTL1 (0.55) | YAP1POLBL3MBTL1 | |
| SCHEMBL19982080 | 0.80 | YAP1 (0.76) | YAP1P2RX7 | |
| SCHEMBL11338761 | 0.80 | FAAH (0.64) | YAP1 | |
| SCHEMBL23853721 | 0.79 | BACE1 (0.56) | P2RX7BACE1L3MBTL1SYK | |
| SCHEMBL23853723 | 0.79 | BACE1 (0.56) | P2RX7BACE1L3MBTL1SYK | |
| SCHEMBL272157 | 0.79 | ATM (0.64) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |