SCHEMBL94839

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5543735	0.81	HPGD (0.61)	HPGDALDH1A1MAPTMEN1LMNA
	SCHEMBL94864	0.76	PPARG (0.49)	TSHRMAPK1HPGDALDH1A1MAPT
	SCHEMBL2960979	0.75	USP2 (0.58)	TSHRMAPK1HPGDALDH1A1MAPT
	SCHEMBL95412	0.75	HDAC1 (0.52)	OPRM1OPRD1OPRK1HPGDALDH1A1
	SCHEMBL96528	0.72	LPAR1 (0.54)	OPRM1OPRD1HPGDALDH1A1MAPT
	SCHEMBL94674	0.71	ALDH1A1 (0.68)	ALDH1A1MAPTLPAR1LPAR5LMNA
	SCHEMBL95772	0.71	HDAC1 (0.52)	LPAR1LPAR5MEN1KMT2AHDAC1
	SCHEMBL5703500	0.71	HPGD (0.73)	HPGDALDH1A1MAPTMEN1LMNA
	SCHEMBL25138742	0.71	HDAC1 (0.71)	TSHRMAPK1OPRD1HPGDALDH1A1
	SCHEMBL5543209	0.71	MLYCD (0.62)	TSHROPRD1HPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.