Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.54 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.54 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974690 | 0.84 | MEN1 (0.66) | MEN1KMT2ATACR1ALDH1A1HPGD | |
| SCHEMBL6247380 | 0.78 | LPAR1 (0.56) | LPAR1LPAR5MEN1KMT2ACYP1A2 | |
| SCHEMBL17276760 | 0.77 | TSPO (0.59) | TSPOMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6248102 | 0.76 | ALDH1A1 (0.58) | LPAR1LPAR5MEN1KMT2ACYP1A2 | |
| SCHEMBL5543735 | 0.76 | HPGD (0.61) | MEN1KMT2ACYP1A2HSP90AA1HSP90AB1 | |
| SCHEMBL11329375 | 0.74 | ACHE (0.55) | TSPOMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL94839 | 0.72 | TSHR (0.48) | LPAR1LPAR5MEN1KMT2AOPRM1 | |
| SCHEMBL6247420 | 0.72 | HPGD (0.62) | LPAR1LPAR5TSPOMEN1KMT2A | |
| SCHEMBL94368 | 0.71 | HDAC1 (0.77) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL10013764 | 0.71 | CYP1A2 (0.78) | TSPOMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |