SCHEMBL9484222

SCHEMBL9484222

CCOC(=O)CN(C(=O)Cc1ccccc1)C1CC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
CTSD P07339 1/20 0.45
TP53 P04637 2/20 0.44
OPRM1 P35372 3/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
LTA4H P09960 1/20 0.42
PPID Q08752 1/20 0.42
MAPK8 P45983 1/20 0.41
MAPK9 P45984 1/20 0.41
MAPK10 P53779 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601798 0.82 L3MBTL1 (0.64) L3MBTL1LMNAMEN1KMT2ACTSD
SCHEMBL9002637 0.82 MEN1 (0.43) L3MBTL1MEN1KMT2ATP53POLB
SCHEMBL13434093 0.80 CCR5 (0.53) L3MBTL1LMNAMEN1KMT2ACTSD
SCHEMBL9483944 0.80 ALDH1A1 (0.51) MEN1KMT2APOLBMAPTGAA
SCHEMBL9484627 0.79 ALDH1A1 (0.53) MEN1KMT2APOLBMAPTGAA
SCHEMBL9483905 0.78 ALDH1A1 (0.52) L3MBTL1MEN1KMT2APOLBMAPT
SCHEMBL9368266 0.77 NLRP3 (0.42) MEN1KMT2APOLBGAA
SCHEMBL5049557 0.77 L3MBTL1 (0.74) L3MBTL1LMNAMEN1KMT2ACTSD
SCHEMBL9366543 0.75 SMN1; SMN2 (0.56) POLBPPIDGAA
Encyprate SCHEMBL122353 0.75 L3MBTL1 (0.55) L3MBTL1LMNACTSDOPRM1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5191089-A Herbicides for weeds that don't harm soybeans, corn, cotton or barley BAYER AKTIENGESELLSCHAFT (DE) 1993-03-02 US disclosed