Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777799 | 0.84 | KDM4E (0.48) | KDM4EALPLGAAPTPN1MEN1 | |
| SCHEMBL6547550 | 0.81 | KDM4E (0.46) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL10533759 | 0.79 | KDM4E (0.44) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL24023042 | 0.77 | KDM4E (0.46) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL19880330 | 0.77 | ALDH1A1 (0.38) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL29350007 | 0.76 | ALDH1A1 (0.59) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL27953 | 0.76 | ALDH1A1 (0.59) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL25302086 | 0.76 | ALDH1A1 (0.59) | KDM4EALPLGAAPTPN1ALDH1A1 | |
| SCHEMBL8960172 | 0.76 | TGM2 (0.39) | — | |
| SCHEMBL18431869 | 0.76 | KDM4E (0.42) | KDM4EALPLGAAPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5239052-A | Heating aromatic disulfide in the presence of an aromatic halide | HAY ALLAN S (CA) | 1993-08-24 | — | — | US | disclosed |