SCHEMBL8960172

SCHEMBL8960172

Ic1ccc(I)c(-c2cc(I)ccc2I)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.39
CES1 P23141 1/20 0.39
CASP3 P42574 1/20 0.37
TDP2 O95551 2/20 0.35
ERN1 O75460 1/20 0.32
TTR P02766 1/20 0.32
NOS1 P29475 1/20 0.31
ADRA2A P08913 1/20 0.30
PNMT P11086 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3314589 0.81 BACE1 (0.44) TGM2CES1
SCHEMBL24179471 0.79 NOS1 (0.31) NOS1
SCHEMBL5682246 0.77 ACHE (0.36) TGM2CES1CASP3
SCHEMBL9484223 0.76 KDM4E (0.43)
SCHEMBL180319 0.76
SCHEMBL29352355 0.76
SCHEMBL456148 0.69
SCHEMBL1350393 0.69
SCHEMBL9566145 0.69
SCHEMBL180221 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110901-A Polythioethers PHILLIPS PETROLEUM COMPANY (US) 1992-05-05 US claimed
US-5077374-A Reacting sulfur and a diphenyl ether in a polyhaloaromatic sol vent using a Friedel-crafts catalyst to obtain a polyphenoxathiinylene sulfide; heat resistance; circuits; capacitors PHILLIPS PETROLEUM COMPANY (US) 1991-12-31 US claimed
US-12577376-B2 Molded articles with laser-formed pattern Celanese Interntaional Corporation (US) 2026-03-17 US disclosed
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide TICONA LLC (US) 2026-02-12 US disclosed
US-20260042903-A1 Laser Transmissive Polyarylene Sulfide Composition TICONA LLC (US) 2026-02-12 US disclosed
EP-4662727-A1 NONAQUEOUS ELECTROCHEMICAL BATTERY CONTAINING A SEALING MEMBER Ticona LLC (US) 2025-12-17 EP disclosed
EP-4626738-A1 PYROTECHNIC SWITCH FOR AN ELECTRIC VEHICLE Ticona LLC (US) 2025-10-08 EP disclosed
EP-4626953-A1 HYDROLYTICALLY STABLE POLYARYLENE SULFIDE COMPOSITION Ticona LLC (US) 2025-10-08 EP disclosed
US-20250289956-A1 Polymer Composition With Improved Thermal Shock Resistance TICONA LLC 2025-09-18 US disclosed
US-20250250422-A1 Polyarylene Sulfide Composition With Improved Crystallization Properties TICONA LLC 2025-08-07 US disclosed
EP-2836555-B1 DYNAMICALLY VULCANIZED POLYARYLENE SULFIDE COMPOSITION TICONA LLC (US) 2025-07-09 EP disclosed
EP-0073526-A1 A method for the preparation of poly(arylene sulfide) PHILLIPS PETROLEUM COMPANY (US) 1983-03-09 EP disclosed
EP-0073525-A1 A method in the preparation of poly(arylene sulfide) PHILLIPS PETROLEUM COMPANY (US) 1983-03-09 EP disclosed
US-4371671-A Controlled, elevated pressure dehydration of poly(arylene sulfide) prepolymerization mixture PHILLIPS PETROLEUM COMPANY (US) 1983-02-01 US disclosed
US-4368321-A Elevated, declining pressure dehydration of poly(arylene sulfide) prepolymerization mixture PHILLIPS PETROLEUM COMPANY (US) 1983-01-11 US disclosed
US-4350810-A Preparation of branched chain arylene sulfide polymer PHILLIPS PETROLEUM COMPANY (US) 1982-09-21 US disclosed
US-4282347-A AGING, RESISTANT FIBERS PHILLIPS PETROLEUM COMPANY (US) 1981-08-04 US disclosed
US-4116947-A FROM P-DIHALOBENZENE, POLYHALO AROMATIC COMPOUND, ALKALI METAL SULFIDE, N-ALKYL LACTAM AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-09-26 US disclosed
US-4089847-A Temperature programming in the production of arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1978-05-16 US disclosed
US-4064114-A Production of arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042903-A1 Laser Transmissive Polyarylene Sulfide Composition TRPC5, TRPC3, TRPC7 TGM2 2381/4885CES1 3816/4885CASP3 2050/4885
US-12577376-B2 Molded articles with laser-formed pattern LAS1L, PIM2, YES1 TGM2 4120/4885CES1 4724/4885CASP3 1534/4885
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide SLC39A3, SLC39A11, SLC39A14 TGM2 1320/4885CES1 2731/4885CASP3 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.