Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487166 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9485669 | 0.87 | KCNH2 (0.44) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL9486675 | 0.85 | KCNH2 (0.52) | CTSVCTSLALDH1A1MEN1KMT2A | |
| SCHEMBL9486871 | 0.77 | MAPT (0.53) | ALDH1A1PKMGAAHTTMAPK1 | |
| SCHEMBL283212 | 0.75 | MAPK1 (0.60) | GAAHTTMAPK1NPSR1TDP1 | |
| SCHEMBL9485957 | 0.74 | OXER1 (0.51) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL9485963 | 0.74 | KCNH2 (0.51) | CTSVCTSLALDH1A1MEN1KMT2A | |
| SCHEMBL9486120 | 0.74 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL9486113 | 0.73 | KCNH2 (0.54) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL21264516 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |