Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486757 | 0.89 | MAPT (0.53) | MAPTCNR1ACHECNR2HTT | |
| SCHEMBL9485957 | 0.85 | OXER1 (0.51) | MAPTCNR1ACHECNR2MAPK1 | |
| SCHEMBL9487366 | 0.83 | PLA2G4A (0.47) | MAPTPLA2G4A | |
| SCHEMBL9485442 | 0.77 | CTSV (0.49) | MAPTCNR2MAPK1HTTGAA | |
| SCHEMBL9485983 | 0.74 | OXER1 (0.50) | MAPTCNR1ACHECNR2MAPK1 | |
| SCHEMBL9486675 | 0.74 | KCNH2 (0.52) | MAPTCNR2MAPK1HTTGAA | |
| SCHEMBL283212 | 0.74 | MAPK1 (0.60) | MAPK1HTTGAANPSR1TDP1 | |
| SCHEMBL9486236 | 0.73 | OXER1 (0.53) | MAPTHTTGAANPSR1ALDH1A1 | |
| SCHEMBL9485938 | 0.73 | MAPK1 (0.60) | MAPTCNR2MAPK1HTTGAA | |
| SCHEMBL9486713 | 0.72 | OXER1 (0.46) | PLA2G4ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |