Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 7/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487718 | 0.84 | ALDH1A1 (0.44) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9487839 | 0.84 | ALDH1A1 (0.38) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9488967 | 0.81 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9487712 | 0.80 | ALDH1A1 (0.41) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9487868 | 0.80 | MEN1 (0.47) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9488030 | 0.79 | KEAP1 (0.49) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| Water SCHEMBL11254873 | 0.78 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL5608458 | 0.78 | TSHR (0.43) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9485995 | 0.77 | ALDH1A1 (0.54) | MAPTLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL9488025 | 0.76 | LTA4H (0.42) | LMNAALDH1A1HTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |