Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641581 | 0.77 | GRM6 (0.52) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10308584 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9487470 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL1720717 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11064868 | 0.70 | BPTF (0.48) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL10288390 | 0.68 | BPTF (0.39) | ALDH1A1MAPTMEN1KMT2AGRM6 | |
| SCHEMBL21605471 | 0.68 | L3MBTL1 (0.57) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL623186 | 0.67 | GRM6 (0.50) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL27002486 | 0.66 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL1798608 | 0.66 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206375-A | Thiophene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0193885-B1 | THIOPHENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1989-06-14 | — | — | EP | disclosed |
| EP-0193885-A1 | Thiophene derivatives | BASF Aktiengesellschaft (DE) | 1986-09-10 | — | — | EP | disclosed |