Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486871 | 0.89 | MAPT (0.53) | MAPTPKMLMNAPLA2G4ATP53 | |
| SCHEMBL9486236 | 0.84 | OXER1 (0.53) | MAPTLMNAF2RL3TP53MEN1 | |
| SCHEMBL9487366 | 0.80 | PLA2G4A (0.47) | MAPTPLA2G4A | |
| SCHEMBL9486042 | 0.76 | LMNA (0.41) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL9487166 | 0.76 | ALDH1A1 (0.51) | MAPTPKMLMNAMEN1KMT2A | |
| SCHEMBL9400698 | 0.74 | MAPT (0.60) | MAPTLMNAF2RL3MEN1KMT2A | |
| SCHEMBL9485957 | 0.73 | OXER1 (0.51) | MAPTLMNAF2RL3TP53MEN1 | |
| SCHEMBL9400567 | 0.73 | MAPT (0.67) | MAPTLMNAPLA2G4AF2RL3TP53 | |
| SCHEMBL9486050 | 0.72 | CNR2 (0.47) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL282873 | 0.72 | EYA3 (0.65) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223510-A | ALKYLAMINOALKYL DERIVATIVES OF BENZOFURAN, BENZOTHIOPHENE, INDOLE AND INDOLIZINE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1993-06-29 | — | — | US | disclosed |