Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16265428 | 0.92 | MEP1B (0.66) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL15145822 | 0.86 | SMN1; SMN2 (0.78) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL15145807 | 0.86 | SMN1; SMN2 (0.74) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL12617210 | 0.84 | MEP1B (0.64) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL16265637 | 0.82 | MEN1 (0.66) | ALDH1A1MEN1KMT2APOLBTSHR | |
| Benzene SCHEMBL16265417 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBTSHR | |
| SCHEMBL15145832 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL1999171 | 0.79 | MMP12 (0.66) | ALDH1A1MEN1KMT2APOLBMEP1B | |
| SCHEMBL15145830 | 0.79 | MEP1B (0.56) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL2001160 | 0.78 | MMP1 (0.64) | ALDH1A1MEN1KMT2APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260338-A | Sulfonylureas | ELI LILLY AND COMPANY (US) | 1993-11-09 | — | — | US | disclosed |