Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.61 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.61 |
| ▸ | APP | P05067 | 5/20 | 0.59 |
| ▸ | ACHE | P22303 | 5/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384391 | 0.87 | ACHE (0.53) | CASP6CTNNB1TCF7L2APPACHE | |
| SCHEMBL16280667 | 0.83 | CASP6 (0.92) | CASP6CTNNB1TCF7L2APPACHE | |
| SCHEMBL9384603 | 0.81 | KMT2A (0.52) | APPACHELTB4R2RAD52KDM4E | |
| SCHEMBL9386292 | 0.80 | APP (0.64) | APPACHELTB4R2RAD52LMNA | |
| SCHEMBL9385541 | 0.80 | BDKRB1 (0.53) | CASP6CTNNB1TCF7L2APPACHE | |
| SCHEMBL9385562 | 0.79 | BDKRB1 (0.51) | CTNNB1TCF7L2APPACHEBCHE | |
| SCHEMBL21843263 | 0.78 | ACHE (0.62) | CTNNB1TCF7L2APPACHEBCHE | |
| SCHEMBL9709750 | 0.78 | DHODH (0.59) | LTB4R2KDM4EPPARG | |
| SCHEMBL9385126 | 0.78 | AGTR2 (0.69) | APPKMT2ASIRT5 | |
| SCHEMBL9386452 | 0.77 | NR2F2 (0.64) | LTB4R2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | claimed |