Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | BRS3 | P32247 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709741 | 0.95 | KDM4E (0.57) | DHODHLTB4R2AGTR1AGTR2PLK1 | |
| SCHEMBL9709740 | 0.92 | LTB4R2 (0.51) | DHODHLTB4R2AGTR1AGTR2PPARG | |
| SCHEMBL3058636 | 0.85 | CD38 (0.56) | LTB4R2 | |
| SCHEMBL7834869 | 0.84 | DHODH (0.59) | DHODHAGTR1AGTR2BRS3PPARG | |
| Hydrochloric Acid SCHEMBL9494706 | 0.84 | CD38 (0.55) | LTB4R2 | |
| SCHEMBL9709569 | 0.82 | PPARG (0.48) | LTB4R2AGTR1AGTR2PLK1BRS3 | |
| SCHEMBL8505737 | 0.81 | DHODH (0.55) | DHODHAGTR1AGTR2BRS3PPARG | |
| SCHEMBL9709710 | 0.80 | PDE4A (0.51) | AGTR1AGTR2 | |
| SCHEMBL9709862 | 0.79 | BDKRB1 (0.46) | DHODHLTB4R2AGTR1AGTR2 | |
| SCHEMBL9709650 | 0.79 | KDM4E (0.49) | LTB4R2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | claimed |
| WO-1992022533-A1 | 4-AMINOQUINOLINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UPJOHN COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |