Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380964 | 1.00 | CTSS (0.53) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL9487560 | 1.00 | CTSS (0.53) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL9713347 | 1.00 | CTSS (0.53) | CTSSCTSLATMCTSKCA12 | |
| Water SCHEMBL10978142 | 0.99 | CTSS (0.55) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL7324724 | 0.90 | SLC15A1 (0.53) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL7324719 | 0.90 | SLC15A1 (0.53) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL7328660 | 0.87 | LTA4H (0.55) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL7328656 | 0.87 | LTA4H (0.55) | CTSSCTSLATMCTSKCA12 | |
| SCHEMBL10504358 | 0.84 | CA12 (0.47) | CTSSCTSLCTSKCA12CA1 | |
| SCHEMBL20272571 | 0.83 | CTSK (0.55) | CTSSCTSLATMCTSKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60226855-A | — | — | None | — | — | JP | disclosed |
| US-5194604-A | PROCESS AND INTERMEDIATES FOR BETA-LACTAMS HAVING AMINOTHIAZOLE(IMINOOXYACETIC ACID)ACETIC ACID SIDECHAINS | E. R. SQUIBB & SONS, INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0464705-A1 | Process and intermediates for Beta-lactams having aminothiazole (iminooxyacetic acid)acetic acid sidechains | E.R. SQUIBB & SONS, INC. (US) | 1992-01-08 | — | — | EP | disclosed |
| JP-S60226855-A | N-BENZYLOXYCARBONYL-L-THREONINAMIDE HEMIHYDRATE AND PREPARATION THEREOF | NIPPON KAYAKU CO LTD | 1985-11-12 | — | — | JP | disclosed |