SCHEMBL9487582

SCHEMBL9487582

COc1ccc(OC)c(Sc2cc(OC)ccc2OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
CA14 Q9ULX7 1/20 0.60
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 2/20 0.52
THRB P10828 1/20 0.52
TYMS P04818 2/20 0.47
EGFR P00533 1/20 0.47
KDR P35968 1/20 0.47
CYP1A1 P04798 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP1B1 Q16678 2/20 0.47
CYP3A4 P08684 1/20 0.47
PTGIR P43119 1/20 0.47
LRRK2 Q5S007 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663217 1.00 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL9193213 0.86 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL2887157 0.85 PTGIR (0.50) CA12CA1CA2CA7CA9
SCHEMBL11612722 0.84 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL31345518 0.83 MAPT (0.58) CA12CA1CA2CA7CA9
SCHEMBL8738414 0.83 MAPT (0.58) CA12CA1CA2CA7CA9
SCHEMBL1918226 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL9770291 0.81 ACHE (0.48) CA12CA1CA2CA7CA9
SCHEMBL9770336 0.81 LTA4H (0.53) CA12CA1CA2CA7CA9
Nitrogen SCHEMBL10783880 0.80 MAPT (0.55) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed