SCHEMBL9487828

SCHEMBL9487828

CC([SiH3])=C(C)c1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ALDH1A1 P00352 4/20 0.46
POLB P06746 2/20 0.43
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.38
ERCC5 P28715 1/20 0.37
FEN1 P39748 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9824671 0.79 CES2 (0.50) CES2CES1ALDH1A1POLBTSHR
SCHEMBL1431970 0.75 CES2 (0.56) CES2CES1ALDH1A1POLBTSHR
SCHEMBL5408652 0.75 CES2 (0.56) CES2CES1ALDH1A1POLBTSHR
SCHEMBL10528507 0.74 TSHR (0.41) ALDH1A1POLBTSHRHPGDERCC5
SCHEMBL10768438 0.73 CES2 (0.54) CES2CES1ALDH1A1POLBTSHR
SCHEMBL9179558 0.73 NPC1 (0.39) ALDH1A1HPGDKMT2A
SCHEMBL6835178 0.72 GABRA1 (0.62) CES2CES1ALDH1A1POLBHPGD
SCHEMBL11743794 0.71 CES2 (0.52) CES2CES1ALDH1A1POLBTSHR
SCHEMBL2585991 0.71 CES2 (0.52) CES2CES1ALDH1A1POLBTSHR
SCHEMBL17187884 0.71 CES2 (0.65) CES2CES1ALDH1A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210143-A Block polymer of nonelastic vinyl aromatic segments. elastic diene segments and a vinyl aromatic compound having halo- or oxysilyl groups or metal halide or oxymetal groups; pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-11 US disclosed
US-5079090-A Pressure sensitive adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-07 US disclosed
EP-0311430-A2 Condensed phase polymers, method of making same, and adhesive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-12 EP disclosed