Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | IL5 | P05113 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654495 | 0.89 | HIF1A (0.63) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL2016044 | 0.86 | NR3C1 (0.73) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL7735905 | 0.84 | HIF1A (0.66) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL2020622 | 0.84 | HIF1A (0.73) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL27780950 | 0.79 | CYP17A1 (0.72) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL28106323 | 0.79 | CYP17A1 (0.72) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL2020336 | 0.78 | HIF1A (0.62) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL7735918 | 0.78 | ALDH1A1 (0.64) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL2019946 | 0.78 | HIF1A (0.61) | HIF1ANR3C2NR3C1CYP3A4PGR | |
| SCHEMBL13768969 | 0.78 | HIF1A (0.64) | HIF1ANR3C2NR3C1CYP3A4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5200518-A | Reduced side effcts | KANGWEON NATIONAL UNIVERSITY (KR) | 1993-04-06 | — | — | US | disclosed |