SCHEMBL9488115

SCHEMBL9488115

C=CCOC(=O)NCCCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 4/20 0.62
TGM2 P21980 1/20 0.56
CHRNB2 P17787 1/20 0.54
CHRNB4 P30926 1/20 0.54
CHRNA3 P32297 1/20 0.54
CHRNA4 P43681 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
TAAR1 Q96RJ0 1/20 0.52
EPHX2 P34913 1/20 0.51
HTT P42858 1/20 0.51
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11442376 0.82 KMT2A (0.51) CASP1NPC1RAB9AHTTKMT2A
SCHEMBL7624194 0.81 CASP1 (0.68) CASP1CYP2D6CYP2C19
SCHEMBL13895513 0.81 HTT (0.74) TGM2CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL20146223 0.81 ERN1 (0.47) CASP1TGM2CHRNB2CHRNB4CHRNA3
SCHEMBL938733 0.80 TGM2 (0.60) TGM2L3MBTL1NPC1RAB9AHTT
SCHEMBL22281731 0.80 L3MBTL1 (0.58) CHRNB2CHRNB4CHRNA3CHRNA4L3MBTL1
SCHEMBL5616002 0.80 L3MBTL1 (0.58) CHRNB2CHRNB4CHRNA3CHRNA4L3MBTL1
SCHEMBL6748819 0.80 HTT (0.72) TGM2CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL11587943 0.80 HDAC3 (0.74) CHRNB2CHRNB4CHRNA3CHRNA4L3MBTL1
SCHEMBL6204298 0.79 TGM2 (0.71) TGM2L3MBTL1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5200547-A From amine or alcohol with carbon dioxide and allyl halide MONSANTO COMPANY (US) 1993-04-06 US disclosed
EP-0477159-A1 Preparation of urethane and carbonate products MONSANTO COMPANY (US) 1992-03-25 EP disclosed