Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488829 | 0.92 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL9489374 | 0.89 | MGAM (0.43) | GAAMGAMSIMGAM2ACHE | |
| SCHEMBL9490254 | 0.88 | LMNA (0.39) | ACHELMNAROCK2ROCK1CYSLTR2 | |
| SCHEMBL9489489 | 0.86 | TDP1 (0.43) | GAAMGAMSIMGAM2SNCA | |
| SCHEMBL9488354 | 0.83 | — | — | |
| SCHEMBL9490136 | 0.83 | TRPV1 (0.41) | GAAACHESNCAMEN1KMT2A | |
| SCHEMBL9488414 | 0.83 | TRPV1 (0.41) | GAAACHESNCAMEN1KMT2A | |
| SCHEMBL9488477 | 0.82 | LMNA (0.39) | LMNA | |
| SCHEMBL9489442 | 0.81 | — | — | |
| SCHEMBL10470034 | 0.81 | MGAM (0.41) | GAAMGAMSIMGAM2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | claimed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | claimed |
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |