Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490452 | 0.93 | KMT2A (0.41) | KMT2ARAB9A | |
| SCHEMBL9488371 | 0.86 | GAA (0.43) | KMT2AGAAMGAMSIMGAM2 | |
| SCHEMBL9490939 | 0.84 | KMT2A (0.40) | KMT2ARAB9A | |
| SCHEMBL9489892 | 0.84 | KMT2A (0.45) | KMT2AALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9488909 | 0.84 | KMT2A (0.45) | KMT2AALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9528078 | 0.80 | CYSLTR2 (0.41) | GAAMGAMSIMGAM2 | |
| SCHEMBL9488829 | 0.79 | MEN1 (0.40) | KMT2A | |
| SCHEMBL9489487 | 0.79 | CYSLTR2 (0.60) | — | |
| SCHEMBL9489374 | 0.78 | MGAM (0.43) | GAAMGAMSIMGAM2 | |
| SCHEMBL9490929 | 0.76 | KMT2A (0.43) | TDP1KMT2AGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |