Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9489442 | 0.92 | — | — | |
| SCHEMBL9488371 | 0.89 | GAA (0.43) | MGAMGAASIMGAM2CYSLTR2 | |
| SCHEMBL9491500 | 0.88 | CYSLTR2 (0.38) | MGAMGAASIMGAM2CYSLTR2 | |
| SCHEMBL9488888 | 0.83 | ACACB (0.39) | ROCK2ROCK1 | |
| SCHEMBL9488351 | 0.83 | ACACB (0.39) | ACHEROCK2ROCK1 | |
| SCHEMBL9489984 | 0.82 | PLA2G4A (0.37) | — | |
| SCHEMBL9488829 | 0.81 | MEN1 (0.40) | — | |
| SCHEMBL9528078 | 0.79 | CYSLTR2 (0.41) | MGAMGAASIMGAM2CYSLTR2 | |
| SCHEMBL10470034 | 0.78 | MGAM (0.41) | MGAMGAASIMGAM2CYSLTR2 | |
| SCHEMBL9489489 | 0.78 | TDP1 (0.43) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337766-B1 | HETERA-ALIPHATIC CARBOXAMIDES | ICI AMERICAS INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5041460-A | Antiallergens, antiinflammatory agents and leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0337766-A1 | Hetera-aliphatic carboxamides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |