Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000358 | 0.92 | CHAT (0.42) | CHATHDAC8 | |
| Iodide SCHEMBL30020692 | 0.90 | CHAT (0.44) | CHATHDAC8 | |
| SCHEMBL28323073 | 0.72 | CHAT (0.42) | CHAT | |
| SCHEMBL10550719 | 0.72 | ACHE (0.39) | ACHEHDAC8 | |
| SCHEMBL11066663 | 0.70 | KDM4E (0.49) | CHAT | |
| SCHEMBL26485003 | 0.69 | RAB9A (0.43) | CHATACHE | |
| SCHEMBL10548005 | 0.68 | TDP1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL3325237 | 0.68 | KDM4E (0.51) | CHAT | |
| SCHEMBL25704729 | 0.68 | CHAT (0.49) | CHATACHE | |
| SCHEMBL28601827 | 0.66 | ALDH1A1 (0.42) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127992-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1993-01-13 | — | — | EP | disclosed |
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |
| EP-0127992-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1984-12-12 | — | — | EP | disclosed |