Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662396 | 0.86 | MAPT (0.46) | KDM4EL3MBTL1LMNARAB9ARECQL | |
| SCHEMBL636993 | 0.86 | MAPT (0.46) | KDM4EL3MBTL1LMNARAB9ARECQL | |
| SCHEMBL14247549 | 0.79 | SRC (0.46) | KDM4ETSHRL3MBTL1RAB9AKMT2A | |
| SCHEMBL5142053 | 0.79 | SRC (0.46) | KDM4ETSHRL3MBTL1RAB9AKMT2A | |
| SCHEMBL187459 | 0.79 | SRC (0.46) | KDM4ETSHRL3MBTL1RAB9AKMT2A | |
| SCHEMBL11243008 | 0.78 | TSHR (0.54) | KDM4ETSHRL3MBTL1MAPK1TP53 | |
| SCHEMBL9487617 | 0.77 | TSHR (0.49) | KDM4ETDP1TSHRL3MBTL1HPGD | |
| SCHEMBL388144 | 0.76 | MTNR1A (0.44) | KDM4ETDP1TSHRL3MBTL1HPGD | |
| SCHEMBL6648182 | 0.76 | MTNR1A (0.44) | KDM4ETDP1TSHRL3MBTL1HPGD | |
| SCHEMBL5072835 | 0.76 | MTNR1A (0.44) | KDM4ETDP1TSHRL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |