Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719081 | 0.79 | ELANE (0.53) | TP53KDM4EHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9820462 | 0.78 | TP53 (0.68) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL10338197 | 0.78 | TP53 (0.68) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL9488596 | 0.78 | KDM4E (0.46) | TSHRTP53KDM4EL3MBTL1MAPK1 | |
| SCHEMBL14367306 | 0.78 | TP53 (0.54) | TSHRTP53PLA2G4BRARBKDM4E | |
| SCHEMBL28472389 | 0.78 | TP53 (0.54) | TSHRTP53PLA2G4BRARBKDM4E | |
| SCHEMBL28459280 | 0.75 | TP53 (0.59) | TSHRTP53PLA2G4BRARBKDM4E | |
| SCHEMBL388144 | 0.74 | MTNR1A (0.44) | TSHRKDM4EHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1092185 | 0.74 | L3MBTL1 (0.85) | TSHRTP53PLA2G4BRARBSMN1; SMN2 | |
| SCHEMBL5072835 | 0.74 | MTNR1A (0.44) | TSHRKDM4EHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356324-A | CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS | DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 1982-10-26 | — | — | US | disclosed |