Acrylamide

Acrylamide

SCHEMBL9490095

C=CC(N)=O.O=c1n(CCO)c(=O)n(CCO)c(=O)n1CCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
FGFR4 P22455 1/20 0.46
CYP3A4 P08684 1/20 0.38
NPSR1 Q6W5P4 1/20 0.35
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
APEX1 P27695 1/20 0.31
HSD17B10 Q99714 1/20 0.30
P2RX3 P56373 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL29353746 0.85 LMNA (0.43) TSHRCYP3A4NPSR1PDE4APDE4B
Acrylic Acid SCHEMBL29353386 0.85 LMNA (0.43) TSHRCYP3A4NPSR1PDE4APDE4B
Acrylic Acid SCHEMBL2396208 0.85 LMNA (0.43) TSHRCYP3A4NPSR1PDE4APDE4B
SCHEMBL12098249 0.80 APEX1 (0.36) TSHRALDH1A1CYP3A4NPSR1APEX1
Formaldehyde SCHEMBL8709282 0.79 CYP3A4 (0.38) TSHRALDH1A1CYP3A4NPSR1PDE4A
SCHEMBL35878 0.79 PDE4A (0.39) TSHRALDH1A1CYP3A4NPSR1PDE4A
SCHEMBL11008643 0.77 CYP3A4 (0.70) CYP3A4NPSR1PDE4APDE4BPDE4C
SCHEMBL9418370 0.77 CYP3A4 (0.70) CYP3A4NPSR1PDE4APDE4BPDE4C
SCHEMBL230828 0.76 TSHR (0.55) TSHRALDH1A1CYP3A4NPSR1HSD17B10
SCHEMBL776295 0.76 TSHR (0.55) TSHRALDH1A1CYP3A4NPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5219923-A High strength polymer gels; resolution AT BIOCHEM, INC. (US) 1993-06-15 US disclosed