Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201774 | 0.90 | MAOA (0.48) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL3810645 | 0.84 | ALDH1A1 (0.55) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL659024 | 0.84 | ALDH1A1 (0.70) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL14299385 | 0.84 | ALDH1A1 (0.70) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL4565540 | 0.84 | HTT (0.61) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL606142 | 0.83 | ALDH1A1 (0.60) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL9491895 | 0.82 | CAMK2A (0.48) | HTTALDH1A1XBP1RAB9A | |
| SCHEMBL9488548 | 0.77 | TAS1R3 (0.46) | MEN1KMT2A | |
| SCHEMBL27547510 | 0.77 | TRPM8 (0.56) | HTTALDH1A1XBP1RAB9ATRPM8 | |
| SCHEMBL8231768 | 0.77 | ALDH1A1 (0.72) | HTTALDH1A1XBP1RAB9ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |