Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.75 |
| ▸ | NQO2 | P16083 | 3/20 | 0.75 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7017220 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL6076911 | 0.85 | TRPV1 (0.67) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL9493664 | 0.83 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL23257562 | 0.83 | TRPV1 (0.61) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL9491533 | 0.82 | POLB (0.56) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL9424922 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL9491217 | 0.81 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| SCHEMBL6078577 | 0.81 | ALDH1A1 (0.51) | MTNR1AMTNR1BNQO2TRPV1 | |
| Agomelatine SCHEMBL15822116 | 0.79 | MTNR1A (0.84) | MTNR1AMTNR1BNQO2TRPV1HTR2C | |
| Agomelatine SCHEMBL1158495 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225442-A | Melatoninergic disorders | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |
| US-5194614-A | COMPOUNDS HAVING A NAPHTHALENE STRUCTURE | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |